Bérénice Collet trained as a stage director at the École Claude Matthieu. She perfected her directing technique with Jean-Yves Ruf and Katie Mitchell. She directed her first opera, Britten's The Little Sweep, at the Théâtre des Champs-Élysées in 2004. In 2007, she directed the world premiere of Verfügbar aux enfers, an operetta set in Ravensbrück by Germaine Tillion at the Théâtre du Châtelet. This was followed by Verdi's Rigoletto in 2011, at the Théâtre Roger Barat in Herblay, and Barber's Vanessa in 2012, co-produced by the Opéra de Metz (2014). This was followed by productions of Mascagni's Zanetto and Weber's Abu Hassan in 2013, and Menotti's The Consul in 2014, revived at the Théâtre de l'Athénée.

For the theatre, she directed L'Infusion by Pauline Sales in 2012, Une femme seule by Dario Fo, Franca Rame in 2015 at the Manufacture des Abbesses in Paris and Un fruit amer in 2016, based on texts by Léonard Vincent. In 2017, she directed Purcell's Fairy Queen at the Conservatoire Hector Berlioz in Paris. In 2018, she collaborated with Katie Mitchell on Marguerite Duras' La Maladie de la mort at Les Bouffes du Nord. She is currently preparing a staging of Médée ou avoir peur des femmes after La Péruse and is collaborating with composer Petter Eckman on the creation of an opera based on Amélie Nothomb's novel Robert des noms propres and with composer Virginia Guastella on Sounds of silence.

She has been artist-in-residence at the Théâtre d'Herblay in Val d'Oise, where she created four opera productions, at the Théâtre de l'Usine in Eragny-sur-Oise, and then at La Maison du Comédien - Maria Casarès in Charente.

Source: Opéra national du Rhin website